| Red light (~670 nm) increases nitric oxide precursors |
In vivo studies showed ~50% increase in plasma NO precursors, improving blood flow in ischemic tissue (PAD model). |
WithPower Clinical Trial Summary |
| Red light promotes NO-dependent vasodilation |
Ex vivo experiments confirmed vasodilation completely inhibited when NO scavengers were applied. |
PMC5699925 |
| NIR light stimulates endothelial nitric oxide synthase (eNOS) |
NIR-II (1064 nm) increased NO via Akt-mediated eNOS activation in endothelial cells at depth. |
PMC9382775 |
| NIR protects heart tissue and aids recovery |
Far-red/NIR reduced ischemia-reperfusion injury even in diabetic conditions, independent of NOS. |
ResearchGate Study |
