| Reduces systemic inflammation and boosts immune resilience |
Pre-exposure to red and NIR light (640 nm & 880 nm) for 30 minutes daily over 10 days reduced neuroinflammation and systemic inflammatory markers following inflammatory challenge in mice. Also maintained white blood cell responsiveness. |
(Greentoes Tucson, PMC) |
| Anti-inflammatory effects at the cellular level |
Review of immune cell studies shows that R/NIR exposure typically triggers anti-inflammatory responses via modulation of reactive oxygen species (ROS), nitrogen oxide (NO), and interleukins—depending on treatment parameters. |
(PubMed) |
| Stimulates immune cell activity (white blood cells) |
In vitro studies found that infrared laser exposure increases both phagocytic activity and chemotactic response of human leukocytes—a critical boost for innate immune defense. |
(MedCentral) |
| Promotes regulatory immune responses (T-cells) |
Photobiomodulation encourages the differentiation of naive T-cells into regulatory T cells (Tregs), which help balance immune responses and reduce excessive inflammation. |
(PMC) |
| Modulates immune signaling via skin exposure |
A literature review suggests that visible and infrared radiation applied to skin can influence both local and systemic immune responses—further supporting the immune-modulatory role of light therapy. |
(Wiley Online Library) |
